Recurrent urinary tract bleeding

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Recurrent urinary tract bleeding

An 83-year-old anemic male, Jose
Admitted to a local hospital
Recurrent urinary tract bleeding
Infection associated with prostatitis
Question 1: How can these conditions affect the hematopoietic system?
Jose’s CBC upon admission
RBC: 4.15 × 1012/L
Hb: 81 g/L
Hct: 0.26 L/L
Platelet: 174 × 109/L
WBC: 2.8 × 109/L
Question 2: How would you describe his anemia morphologically?
Reflex testing for anemia on Jose followed based on the CBC results. Recurrent urinary tract bleeding
Reticulocyte count: 2.6%
Serum iron: 18 mcg/dL
TIBC: 425 mcg/dL
Question 3: Calculate % saturation.
Question 4: Is this value normal, decreased, or increased?
Question 5: What disease, if any, does this value suggest?
Question 6: How do the patient’s iron study results help in differentiating the diagnosis of iron deficiency from ACD?
Question 7: What additional test that was not done would be most helpful in this case?
Question 8: Do the iron studies in Jose (serum iron 18 mcg/dL, TIBC 425 mcg/dL) suggest sideroblastic anemia? Why or why not?
Question 9: Based on the reticulocyte count, is his bone marrow having an adequate response to the marrow, why or why not? Recurrent urinary tract bleeding

George, a 50-year-old male, visited his doctor when he noticed the whites of his eyes appeared yellow and he had dark urine. His CBC revealed a hemoglobin of 31 g/L.
Given his clinical description, name at least 2 lab tests that should be ordered to assist in diagnosis?
George’s only complaint was the yellow color of his eyes and dark urine. His CBC:
Hb 3.1 g/dL, Hct 0.08 L/L
RBC count 0.71 × 1012/ L
RDW 21.6
Reticulocytes 22%
Calculate the erythrocyte indices.
Question 3: Does the information given support acute or chronic blood loss? What is the significance of the RDW? Recurrent urinary tract bleeding
George’s RBC count is 0.7 × 1012/L and his reticulocyte count is 22%.
Question 4: Calculate his absolute reticulocyte count. Is this count increased, decreased, or normal?
George’s blood smear revealed marked spherocytosis.
Question 5: Explain the importance of this finding.
Question 6: Explain George’s abnormal indices.
Question 7: Classify George’s anemia morphologically.
George had a test done that revealed antibodies and complement coating his red blood cells, this supports a diagnosis of immune hemolytic anemia.
Question 8: Classify George’s anemia functionally.
Question 9: Why were George’s eyes yellow?
Question 10: Was this anemia chronic or acute and why? Recurrent urinary tract bleeding